Mounjaro Dosage Chart 2026
Complete Mounjaro titration schedule from 2.5mg to 15mg for diabetes and weight loss, plus affordable compounded tirzepatide through Coreage Rx.
What Is Mounjaro?
Quick Facts:
- Active Ingredient: Tirzepatide
- FDA-Approved For: Type 2 diabetes management
- Off-Label Use: Weight loss (widely prescribed for this purpose)
- Medication Type: GLP-1/GIP receptor agonist (dual-action)
- Administration: Once-weekly subcutaneous injection
- Manufacturer: Eli Lilly
- Same Active Ingredient As: Zepbound (weight loss version)
Mounjaro is FDA-approved for improving blood sugar control in adults with type 2 diabetes. However, because it contains the same active ingredient as Zepbound (tirzepatide) and produces significant weight loss, many doctors prescribe it off-label for weight management—especially when insurance won't cover Zepbound.
Mounjaro is unique because it targets TWO hormones (GLP-1 and GIP) rather than just one, making it potentially more effective than semaglutide-based medications for both diabetes and weight loss.
Complete Mounjaro Dosage Chart
The FDA-approved titration schedule gradually increases your dose over 20 weeks to optimize blood sugar control, minimize side effects, and maximize weight loss.
| Week/Month | Dosage | Purpose |
|---|---|---|
| Weeks 1-4 | 2.5 mg | Starting dose. Allows your body to adjust to the medication and minimizes initial side effects. |
| Weeks 5-8 | 5 mg | First increase. First maintenance dose. Many patients see good blood sugar control and weight loss at this level. |
| Weeks 9-12 | 7.5 mg | Second increase. Enhanced blood sugar control and weight loss. Some patients stay here long-term. |
| Weeks 13-16 | 10 mg | Third increase. Most common maintenance dose for patients needing additional glycemic control and weight loss. |
| Weeks 17-20 | 12.5 mg | Fourth increase. Near-maximum dosing for patients still needing better control. |
| Week 21+ | 15 mg | Maximum dose. Highest FDA-approved dose for maximum blood sugar control and weight loss effects. |
⚠️ Important Dosing Notes
- Each dose increase should occur after at least 4 weeks on the previous dose
- Your doctor may delay increases if you experience significant side effects
- Many patients achieve excellent results at 5mg, 7.5mg, or 10mg and don't need 15mg
- The 2.5mg starting dose IS therapeutic (unlike Ozempic's 0.25mg) but higher doses are more effective
- Inject once weekly on the same day each week, any time of day
- Can be injected in abdomen, thigh, or upper arm
- Same dosing schedule as Zepbound (weight loss version)
Mounjaro for Weight Loss: Off-Label Use
While Mounjaro is only FDA-approved for diabetes, it's widely prescribed off-label for weight loss because:
- It contains the same active ingredient (tirzepatide) as Zepbound
- Clinical trials showed 15-21% average body weight loss
- It's more effective than semaglutide-based drugs (Ozempic/Wegovy) for many people
- Insurance is more likely to cover Mounjaro (for diabetes) than Zepbound
- Uses the exact same dosing schedule as Zepbound
Mounjaro vs Zepbound:
They're essentially identical medications:
- Same active ingredient: Both contain tirzepatide
- Same dosing: Both use 2.5mg to 15mg weekly schedule
- Same results: Identical weight loss effects
- Only difference: FDA-approved indication (Mounjaro for diabetes, Zepbound for weight loss)
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Why pay $1,000-1,200/month for brand-name Mounjaro when you can get the same active ingredient for 50-70% less?
Mounjaro vs Compounded Tirzepatide (Coreage Rx)
| Factor | Mounjaro (Brand) | Coreage Rx (Compounded) ⭐ |
|---|---|---|
| Active Ingredient | Tirzepatide | Tirzepatide |
| Monthly Cost (No Insurance) | $1,000-1,200 | 50-70% Less |
| FDA-Approved For | Diabetes only | Weight Loss (Primary) |
| Dosing Protocol | 2.5mg to 15mg | 2.5mg to 15mg |
| Physician Supervision | ✓ | ✓ |
| Telehealth Option | Varies | 100% Online |
| Weight Loss Results | 15-21% body weight | 15-21% body weight |
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My Experience with Compounded Tirzepatide
I don't have diabetes, so getting Mounjaro covered by insurance wasn't an option. Brand-name Zepbound was $1,200/month. That's when I discovered compounded tirzepatide through Coreage Rx.
I followed this exact dosing schedule: started at 2.5mg, increased to 5mg after 4 weeks, then 10mg (where I am now). The appetite suppression was powerful from week 1. I lost 16 pounds in 10 weeks.
Same tirzepatide, same dosing, same results—at a price I can actually afford.
Frequently Asked Questions
Is Mounjaro better than Ozempic for weight loss?
Clinical trials suggest Mounjaro (tirzepatide) produces more weight loss than Ozempic (semaglutide)—averaging 15-21% vs 15-17% body weight loss. Mounjaro targets two hormones (GLP-1 and GIP) instead of one, making it potentially more effective.
Can I use Mounjaro for weight loss if I don't have diabetes?
Yes, many doctors prescribe Mounjaro off-label for weight loss. However, insurance typically won't cover it without a diabetes diagnosis. Compounded tirzepatide through services like Coreage Rx offers the same medication for weight loss at lower cost.
What's the difference between Mounjaro and Zepbound?
They're the same medication with the same dosing schedule. Mounjaro is FDA-approved for type 2 diabetes, while Zepbound is FDA-approved for chronic weight management. Same active ingredient (tirzepatide), same results.
How much weight can I lose on Mounjaro?
Clinical trials showed patients lost an average of 15-21% of their body weight over 72 weeks. For a 200-pound person, that's 30-42 pounds. Results vary based on dose reached, adherence, lifestyle factors, and individual response.
Does insurance cover Mounjaro?
Insurance typically covers Mounjaro for type 2 diabetes but not for weight loss alone. Without insurance or diabetes, you'll pay $1,000-1,200/month unless you use compounded alternatives that cost 50-70% less.
Get Tirzepatide at an Affordable Price
Skip the $1,200/month brand-name price. Get physician-supervised compounded tirzepatide through Coreage Rx.
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⚠️ Important Medical Information
This article is for informational purposes only. Mounjaro (tirzepatide) is a prescription medication requiring physician supervision.
Read the full Medical Disclaimer and Affiliate Disclosure.