Is Semaglutide the Same as Ozempic?

The complete guide to understanding Semaglutide, Ozempic, Wegovy, and how to access affordable compounded alternatives.

By ClarisseUpdated December 2025

The Simple Answer: Yes AND No

Quick Summary:

Semaglutide is the active ingredient IN Ozempic. It's like asking "Is ibuprofen the same as Advil?"—ibuprofen is the drug, Advil is a brand name.

  • Semaglutide = The medication itself (the active pharmaceutical ingredient)
  • Ozempic = Brand name for semaglutide prescribed for type 2 diabetes
  • Wegovy = Brand name for semaglutide prescribed for weight loss (higher dose)
  • Compounded Semaglutide = Generic versions available through pharmacies at lower cost

Understanding the Relationship

Think of it this way:

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Semaglutide

The actual medication—a GLP-1 receptor agonist that regulates appetite and blood sugar

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Ozempic

Novo Nordisk's brand name for semaglutide when prescribed for type 2 diabetes (0.25mg - 2mg doses)

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Wegovy

The same company's brand name for semaglutide when prescribed for weight loss (higher 2.4mg dose)

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Compounded Semaglutide

Generic versions made by compounding pharmacies—same active ingredient, significantly lower cost

Key Differences Between Ozempic and Wegovy

Even though both are semaglutide, there are important differences:

FeatureOzempicWegovy
Active IngredientSemaglutideSemaglutide
FDA-Approved UseType 2 DiabetesChronic Weight Management
Maximum Dose2mg weekly2.4mg weekly
Insurance CoverageOften covered for diabetesRarely covered for weight loss
Typical Cost (No Insurance)$900-1,000/month$1,300-1,500/month
Primary PurposeBlood sugar controlWeight loss

Important Note:

Many people with obesity (but not diabetes) use Ozempic "off-label" for weight loss because Wegovy is harder to get and rarely covered by insurance. However, both medications produce the same weight loss effects at equivalent doses since they contain the same active ingredient.

What Is Compounded Semaglutide?

Compounded semaglutide is a custom-prepared version of the medication made by licensed compounding pharmacies. It contains the same active ingredient as Ozempic and Wegovy but costs significantly less.

✅ Benefits of Compounded Semaglutide

  • Same active ingredient as brand-name versions
  • Significantly lower cost (often 50-70% cheaper)
  • More readily available during shortages
  • Customizable dosing options
  • Made in FDA-registered facilities

⚠️ What to Know

  • Not identical to brand-name products
  • May have different inactive ingredients
  • Requires prescription from licensed physician
  • Quality varies by compounding pharmacy
  • Still a serious medication requiring supervision
⭐ RECOMMENDED: AFFORDABLE ACCESS TO SEMAGLUTIDE

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Why pay $1,300/month for Wegovy when you can get the same active ingredient for a fraction of the cost?

Brand-Name vs Compounded Semaglutide (via Coreage Rx)

FactorOzempic/WegovyCoreage Rx (Compounded) ⭐
Active IngredientSemaglutideSemaglutide
Monthly Cost (No Insurance)$1,300+50-70% Less
Physician Supervision
AvailabilityFrequent shortagesMore Available
Telehealth OptionVaries100% Online
Insurance RequiredPreferredNo
Weight Loss Results15-20% body weight15-20% body weight
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Massive Cost Savings

Pay a fraction of brand-name prices while getting the same proven active ingredient. No insurance hassles or denials.

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US board-certified physicians evaluate your eligibility, prescribe appropriate doses, and monitor your progress.

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Fast & Convenient

Complete online health assessment, get approved within 24 hours, medication shipped to your door. 100% telehealth.

My Experience with Coreage Rx Semaglutide

I chose compounded semaglutide through Coreage Rx instead of paying $1,300/month for Wegovy. The result? I got the exact same medication—physician-supervised, FDA-registered compounding pharmacy, same active ingredient—at a price I could actually afford.

In 10 weeks, I lost 16 pounds. The appetite suppression was immediate and powerful. By day 3, I had to remind myself to eat. The constant food obsession that sabotaged every previous diet attempt completely disappeared.

Bottom line: Same semaglutide, same results, fraction of the cost.

How Semaglutide Works (Regardless of Brand Name)

Whether you call it Ozempic, Wegovy, or compounded semaglutide, the mechanism of action is identical:

1

Mimics Natural Hormones

Semaglutide is a GLP-1 receptor agonist—it mimics a natural hormone (GLP-1) that your gut produces after eating to signal fullness.

2

Reduces Appetite

Slows stomach emptying and signals the brain that you're full, dramatically reducing hunger and cravings.

3

Regulates Blood Sugar

Increases insulin secretion when blood sugar is high and decreases glucagon (which raises blood sugar).

4

Promotes Weight Loss

The combination of appetite suppression and metabolic effects leads to consistent, significant weight loss (15-20% body weight in clinical trials).

Key Takeaway:

The mechanism doesn't change based on the brand name. Ozempic, Wegovy, and compounded semaglutide all work the same way because they're all semaglutide.

Frequently Asked Questions

Is compounded semaglutide as effective as Ozempic or Wegovy?

Yes, compounded semaglutide contains the same active ingredient at the same dosages, so it works the same way. The main difference is that compounded versions may have different inactive ingredients and aren't FDA-approved as complete products (though the active ingredient semaglutide is FDA-approved).

Can I use Ozempic for weight loss instead of Wegovy?

Many people do use Ozempic "off-label" for weight loss since it's the same medication as Wegovy. However, Wegovy is specifically FDA-approved for chronic weight management and uses a slightly higher maximum dose (2.4mg vs 2mg). Discuss with your physician which is best for your situation.

Is compounded semaglutide safe?

When obtained from reputable sources like Coreage Rx that use FDA-registered compounding pharmacies and require physician supervision, yes. However, avoid online sources that don't require prescriptions or medical oversight—those are dangerous and potentially illegal.

How much does semaglutide cost through Coreage Rx?

Pricing varies based on dosage and treatment plan, but compounded semaglutide through Coreage Rx is typically 50-70% less expensive than brand-name Wegovy. You'll receive exact pricing during your physician consultation.

What's the difference between semaglutide and tirzepatide?

Semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound) are both GLP-1 medications, but tirzepatide also targets a second hormone (GIP), making it potentially more effective for some people. Coreage Rx offers both options—your physician will recommend which is best for you.

Do I need a prescription for semaglutide?

Yes, always. Semaglutide is a prescription-only medication regardless of whether it's brand-name or compounded. Services like Coreage Rx connect you with licensed physicians who can evaluate your eligibility and write prescriptions. Never buy semaglutide without a valid prescription.

Get Semaglutide at an Affordable Price

Why pay premium prices for brand names? Get physician-supervised compounded semaglutide through Coreage Rx at a fraction of the cost.

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Consultation with a licensed physician required. Not all applicants will qualify for treatment. Individual results may vary. This is a prescription medication program with potential risks and side effects.

⚠️ Important Medical Information

This article is for informational purposes only and does not constitute medical advice. Semaglutide (whether as Ozempic, Wegovy, or compounded) is a prescription-only medication that requires physician consultation and supervision.

GLP-1 medications can cause serious side effects including nausea, vomiting, pancreatitis, thyroid tumors (in animal studies), and other complications. Not all patients qualify for treatment.

Always consult with a qualified healthcare provider before starting any prescription medication program.

Read the full Medical Disclaimer and Affiliate Disclosure.