Celebrities on Ozempic

The diabetes drug that became Hollywood's worst-kept weight loss secret. Which celebrities are using Ozempic, and how can regular people access the same medication affordably?

By ClarisseUpdated April 2026

What is Ozempic?

Ozempic is the brand name for semaglutide, originally FDA-approved in 2017 for treating type 2 diabetes at doses up to 2mg weekly. However, doctors quickly noticed a powerful side effect: dramatic weight loss.

When Ozempic went viral in 2022-2023 as Hollywood's "secret weapon" for weight loss, it became nearly impossible to find. The medication was being prescribed "off-label" for weight loss to people without diabetes, creating shortages for diabetic patients who actually needed it.

How Ozempic Became a Celebrity Trend

  • Rapid results: 15-20% body weight loss in months
  • Minimal effort: Appetite suppression means less hunger naturally
  • Once-weekly shot: Convenient self-injection
  • Medically supervised: Prescribed by doctors, not just a "diet"
  • Celebrity word-of-mouth: Spread through Hollywood like wildfire

Important Note: Ozempic is FDA-approved for diabetes, NOT weight loss. For weight loss, the FDA-approved version is Wegovy (same ingredient, higher 2.4mg dose). However, many people use Ozempic off-label because it's often easier to get insurance coverage.

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Celebrities Who've Admitted Using Ozempic

Amy Schumer

Status: Tried it, stopped due to side effects

Comedian Amy Schumer was candid about trying Ozempic for weight loss but stopping because it made her "so sick" she couldn't function or care for her son. She's one of the few celebrities willing to discuss both the appeal and the downsides openly.

Chelsea Handler

Status: Unknowingly prescribed, stopped after learning about it

Talk show host Chelsea Handler revealed on her podcast that her anti-aging doctor prescribed Ozempic without clearly explaining what it was. She stopped taking it after realizing the controversy and Hollywood trend around the medication.

Sharon Osbourne

Status: Used it, lost significant weight

Sharon Osbourne publicly discussed using Ozempic and losing over 40 pounds. She later expressed concerns about losing "too much" weight and warned that the medication can be difficult to stop once started.

Tracy Morgan

Status: Joked about it publicly

Comedian Tracy Morgan made jokes about Ozempic use during stand-up, implying he'd tried it. While delivered as comedy, the specificity suggested firsthand knowledge of the medication.

Celebrities Heavily Speculated to Be Using Ozempic

Disclaimer: The following celebrities have NOT confirmed using Ozempic. Speculation is based on rapid, dramatic weight loss that matches Ozempic's effects.

Kim & Khloe Kardashian

Both sisters' rapid weight loss transformations sparked intense "Ozempic speculation" across social media and tabloids. They've repeatedly denied using it, crediting diet and exercise.

Mindy Kaling

Her noticeable slimming led to Ozempic questions, which she addressed by saying she worked out and ate right—though she acknowledged people wouldn't believe her regardless.

Rebel Wilson

Lost 80 pounds during her "Year of Health." While she credits lifestyle changes, the speed and extent of weight loss led to persistent Ozempic speculation.

Jessica Simpson

100-pound post-pregnancy weight loss sparked questions. She's consistently denied Ozempic use, crediting personal training and diet.

Kyle Richards

The Real Housewives star's weight loss led to constant Ozempic accusations, which she's firmly denied while discussing her intense workout routine.

The "Ozempic Face" Phenomenon

One telltale sign of rapid Ozempic-induced weight loss is "Ozempic face"—a gaunt, aged appearance in the face caused by:

  • Rapid fat loss: Facial fat disappears quickly, causing sagging skin
  • Loss of facial volume: Cheeks hollow out, creating a sunken look
  • Visible aging: Skin can't keep up with rapid fat loss, leading to wrinkles

Many celebrities combat "Ozempic face" with dermal fillers, Botox, and other cosmetic procedures to restore facial volume. This dual approach—Ozempic for body weight, fillers for face—has become standard in Hollywood.

Frequently Asked Questions

Is Ozempic approved for weight loss?

No. Ozempic is FDA-approved only for type 2 diabetes. For weight loss, the FDA-approved version is Wegovy (same ingredient, 2.4mg dose). However, doctors can prescribe Ozempic "off-label" for weight loss, which is legal but not its intended use.

How much does Ozempic cost?

Brand-name Ozempic costs $900-1,200/month without insurance. Insurance often covers it for diabetes but NOT for weight loss. Compounded semaglutide from Coreage Rx costs 50-70% less with no insurance needed.

Can I get Ozempic online?

Yes, through telehealth services. Coreage Rx offers online physician consultations and prescribes compounded semaglutide (same active ingredient) that's shipped to your door. You get the same medication celebrities use at an affordable price.

Why won't celebrities admit to using Ozempic?

Stigma around weight loss drugs, public backlash about using diabetes medication for vanity during shortages, and pressure to appear "naturally" fit all contribute. There's also concern about setting unrealistic expectations for fans.

What happens when you stop taking Ozempic?

Most people regain weight after stopping Ozempic because the appetite suppression ends. Ozempic is meant to be a long-term medication, not a quick fix. Sustainable lifestyle changes are essential for maintaining results.

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⚠️ Important Disclaimer

This article discusses publicly reported celebrity use of Ozempic. Information is based on public statements and media reports. Speculation about unconfirmed celebrity use is clearly labeled.

Ozempic and semaglutide should only be used under medical supervision. Always consult a qualified healthcare provider before starting any prescription medication.

Read the full Medical Disclaimer.

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